| ABSTRACT Objective:To investigate the characteristics and risk etiological factors of drug induced liver injury (DILI) cases in the elderly, and provide information for clinical prevention and treatment. Methods: The clinical data of 45 elderly with DILI were retrospectively analyzed according to their history of medicine, clinical manifestations, underlying diseases, treatment and prognosis. Results: 32 cases of 45 patients were female, male, 13 cases. The primary underlying diseases of these patients were cardiovascular disease, osteoarthrosis, infectious diseases, cold, skin diseases and so on. These 45 cases involved 64 drugs, the top 5 were traditional Chinese medicine, anti inflammatory drugs, cardiovascular drugs, the anti infective drugs and digestive systems drugs. The main clinical manifestations included urine, fatigue, anorexia. 34 patients were cured, 11 patients improved. Conclusion:DILI is dominated by traditional Chinese medicine in the elderly, with various clinical manifestations and favorable prognosis. |
