| ABSTRACT Objective: To discuss the treatment of large doses of vitamin C combined with routine treatment in children with myocarditis is analyzed to investigate the clinical effect in treatment. Methods:86 cases of pediatric myocarditis patients were divided into two groups at random. 43 patients of control group accepted routine treatment, the other 43 patients in the treatment group were given vitamin C 150-200 mg·kg-1 ivd qd on the basis of high dose intravenous drip microbial method,both for a course of 18 month. The myocardial enzyme, cTnI ,T-lymphocyte and the improment of cardiac function of the patients in the two groups were observed. The clinical effect of two groups of patients was compared. Results:The total effective rate was 95.35% in the treatment group;while in the control group the total effective rate was 86.05%.Compared with the control group,the group in patients with clinical effectiveness is higher (P<0.05). In addition, the treatment group of patients with myocardial enzymes, troponin (cTnI),T lymphocyte group of patients as well as the improvement of cardiac function were superior to control group, the differences between the two groups have statistical significance (P<0.05). And, in the process of treatment, two groups of patients had no adverse reaction occurred. Conclusion:In the treatment of pediatric myocarditis, large doses of vitamin C had its reliable curative effect, could not only improve the patient's systemic symptom, and can adjust the immune function, with lower adverse reactions, worthy of clinical use. |
