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莫西沙星序贯疗法治疗支气管肺炎最小成本分析
Cost minimization Analysis of Moxifloxacin Sequential Therapy for the Treatment of Bronchial Pneumonia
  
DOI:
中文关键词:  莫西沙星  支气管肺炎  序贯疗法  最小成本分析
英文关键词:Moxifloxacin  Bronchial pneumonia  Sequential therapy  Cost minnimization analysis
基金项目:
作者单位
郭均平 武警湖北省总队医院药剂科(武汉 430061) 
张金安 武警湖北省总队医院药剂科 
姜林 武警湖北省总队医院呼吸内科
 
胡敏芳 华中科技大学同济药学院 
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中文摘要:
      摘 要 目的:分析与探讨莫西沙星序贯疗法对于支气管肺炎治疗的疗效与经济学效果。方法:选取支气管肺炎患者共57例随机分为2组。观察组(29例)在常规治疗的基础上采用莫西沙星序贯疗法治疗,对照组(28例)在常规治疗的基础上采用莫西沙星400 mg,ivd qd。对比两组患者的临床疗效、症状改善、住院时间、不良反应和成本等指标。结果:观察组临床总有效率为96.55%,对照组为92.86%,两组差异无统计学意义(P>0.05)。观察组的体温正常时间、胸片检查正常时间、咳嗽停止时间较对照组时间短(P<0.05),两组住院时间及不良反应发生率比较,差异无统计学意义(P>0.05)。莫西沙星序贯疗法治疗支气管肺炎成本低于常规疗法。结论:采用莫西沙星序贯疗法治疗支气管肺炎与常规治疗效果相当,但治疗成本较低。
英文摘要:
      ABSTRACT Objective:To analyze and discuss the treatment effect and economic effect of moxifloxacin sequential therapy for the treatment of bronchialpneumonia.Methods:A total of 57 patients which were confirmed by sputum culture with bronchopneumonia caused by bacteria in our hospital from January 2012 to January 2013 were selected and randomly divided into two groups. The observation group 29 cases used moxifloxacin sequential therapy as adjuvant therapy on the basis of conventional treatment, and 28 cases for control group were attached to an intravenous drip with moxifloxacin 400mg each time and once a day on the basis of conventional treatment. The clinical efficacy, improvement of symptoms, length of stay and adverse reaction between two groups were compared. The cost and effect of two kinds of treatments with moxifloxacin were compared and evaluated. Results: The clinical total effective rate of observation group reached 96.55%, and 92.86% in the control group with no statistically significant difference(P>0.05). The time for normal body temperature, normal chest films, stopping cough and average stay in the observation group was shorter than the control group (P<0.05), and there was no statistically significant difference in hospital time (P>0.05).Moreover, the cost of moxifloxacin sequential therapy for the treatment of bronchial pneumonia was lower than the conventionaltreatment. Conclusion:The moxifloxacin sequential therapy has the same effect on the treatment of bronchial pneumoniawith ordinary therapy. Besides, the moxifloxacin sequential therapy has a lower cost and less incidence of adverse reactions.
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