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2008~2013年武汉地区32家医院抗病毒药使用分析
  
DOI:
中文关键词:  抗病毒药  限定日剂量  用药频度  限定日费用  药物利用
英文关键词:Antiviral drugs  DDD  DDDs  DDC  Drug utilization
基金项目:Utilization Analysis of Antiviral Drugs of 32 Hospitals in Wuhan Area during 2008-2013
作者单位
杜艾桦 华中科技大学同济医学院附属同济医院科研处(武汉 430030) 
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中文摘要:
      摘 要 目的:统计武汉地区近6年抗病毒药的使用情况,分析其变化趋势,为合理用药提供依据。方法:统计分析武汉地区32家医院2008~2013年抗病毒药的销售金额、用药频度(DDDs)和限定日费用(DDC)。结果:2008~2013年武汉地区抗病毒药年销售总金额和DDDs逐年上升,年销售金额排在前5位的为恩替卡韦、阿德福韦酯、拉米夫定、替比夫定和更昔洛韦;DDDs排名前5位的是阿德福韦酯、恩替卡韦、利巴韦林、替比夫定、拉米夫定。大多数药物的DDC较为稳定,个别药物如奥司他韦、穿琥宁的DDC波动较大。结论:武汉地区32家医院近6年的抗病毒药使用基本稳定,西药占据了主要市场,其中以疗效较好的恩替卡韦、价格低廉的阿德福韦酯等药品增长迅速,而穿琥宁为代表的中药抗病毒药应用较少。
英文摘要:
      ABSTRACT Objective: To analyze the use trend of antiviral drugs of 32 hospitals in Wuhan area over the past six years and provide reference for the rational drug use. Methods:Analyzing the consumption, DDDs and daily drug cost (DDC) of antiviral drugs in 32 hospitals in Wuhan area from 2008 to 2013. Results: From 2008 to 2013, the total consumption and DDDs of antiviral drugs in Wuhan area were increasing. Entecavir, adefovir, lamivudine, telbivudine and ganciclovir ranked the top 5 in terms of consumption sum; while the top 5 in DDDs were adefovir, entecavir, ribavirin, telbivudine and lamivudine. The DDC of most antiviral drugs were relatively stable,but individual drugs such as oseltamivir and Chuanhuning displayed larger fluctuation in DDC. Conclusion:During the period of 2008 to 2013, the utilization of anti viral drugs of 32 hospitals in Wuhan area is basically stable. Western medicine occupys main market, with effective entecavir and low price adefovir increased rapidly, while Chuanhuning were less used as the representative of the traditional Chinese medicine.
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