| ABSTRACT Objective:To study the 28 cases of adverse reactions of drugs (ADR) caused by Xuebijing injection to find their rules and characteristics, aimed at providing the reference for using of drugs in clinic. Methods:The data of ADR caused by Xuebijing injection in Shandong province during Jan. 1st 2012 to Mar. 31th 2015 was collected and retrospectively analyzed, including patient's conditions (gender, age, primary diseases, ADR history), drug conditions (the route of administration, dosage, combination therapy), ADR time of occurrence, classification and clinical manifestations, the relevance of the evaluation results and disposition of the case outcome. Results:Most serious adverse reactions of drugs caused by Xuebijing injection in patients aged 40 to 49 years old, and more than women. The main adverse performance was respiratory system damage, and occurred after drug using within a short time. After discontinuing and symptomatic treatment, all patients had good prognosis. Conclusion:It should be strengthen the work of serious adverse drug reactions monitoring, and focus on respiratory system injury (rapid onset) caused by Xuebijing injections in clinic in order to ensure drug safety for patients. |
