| ABSTRACT Objective: To understand the scale, rules, and epidemic disease factor of ADR in the district of Wenzhou city. Methods: Conducted statistical analysis by collecting case reports in all counties (cities, and districts) of whole city and analyzed gender, age, ADR type, and distribution of drug dosage. Results:3 612 cases of ADR happened in the whole city within 6 months, involving more than 220 medical organizations; they happened in all age levels: people aging from 11 to 20 occupied 3.82%, which took account for the lowest proportion; people aging from 31 to 40 and from 41 to 50 occupied 15.67% and 15.06% respectively, which took account for the highest proportion, including 1 628 male cases and 1 977 female cases; there were 1 133 cases of new and serious ADR, which occupied 31.36%, including 5 death cases;Of the 3 612 ADR cases, antibacterial drug (44.43%) ranked the first and followed by the Chinese medicine preparation (15.20%); intravenous drip was the most dangerous drug deliver route; ADR involved multiple systems in body, among which skin and appendix damage (37.53%) and alimentary system damage (21.63%) were the most common ones. Conclusion:ADR in antibacterial drug and Chinese medicine preparation happened frequently. We should take a further step to manage usage of antibiotics, strictly grasp the indication of intravenous administration, and improve the safety understanding of people on intravenous administration. |
