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周边虹膜切除术后应用普拉洛芬滴眼液的临床观察
Clinical Observation on the Effects of Pranoprofen Eye Drops in Postoperative Patients with Peripheral Iridectomy
  
DOI:
中文关键词:  周边虹膜切除术  普拉洛芬滴眼液  妥布霉素地塞米松滴眼液
英文关键词:Peripheral iridotomy  Pranoprofen eye drops  Tobramycin and dexamethasone ophthalmic suspension
基金项目:
作者单位
赵嫏嬛 温州市人民医院(浙江温州 325000) 
周陈建 温州市中心医院 
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中文摘要:
      摘 要 目的:探讨普拉洛芬滴眼液在周边虹膜切除术后的应用价值。方法:闭角型青光眼患者行激光周边虹膜切除术62例,随机分成观察组与对照组各31例(31眼)。观察组患者用普拉洛芬滴眼液点眼,对照组患者用妥布霉素地塞米松滴眼液点眼。观察比较两组患者治疗前及治疗1,3,7 d后眼压和各症状体征综合评分变化,以及两组药品不良反应发生情况。结果:两组患者治疗前后平均眼压均无明显变化(P>0.05);治疗后,两组患者眼部综合症状以及体征评分较治疗前明显降低(P<0.01),且观察组治疗后评分明显优于对照组(P<0.05)。两组药品不良反应比较,差异无统计学意义(P>0.05)。结论:周边虹膜切除手术后患者应用普拉洛芬滴眼液安全、有效,可降低激素性高眼压的风险,有临床应用价值。
英文摘要:
      ABSTRACT Objective: To investigate the clinical value of pranoprofen eye drops after peripheral iridectomy surgery.Methods:62 cases of patients who had primary closed angle glaucoma underwent laser peripheral iridectomy, were randomly divided into observation group and control group each 31 cases (31 eyes). The observation group were treated with pranoprofen eye drops, the control group were given tobramycin and dexamethasone ophthalmic suspension. Before and 1,3,7days after treatment, the intraocular pressure and the symptoms and signs comprehensive score changes, and the adverse drug reactions of two groups were compared. Results:There had no obvious change of average intraocular pressure before and after treatment in both groups (P>0.05); After the treatment, the comprehensive eye signs and symptoms score of two groups patients significantly lower than before (P<0.01), and the observation group was significantly better than the control group, the difference was statistically significant (P<0.05). There had no significant difference of adverse drug reactions between the two groups (P>0.05).Conclusion:After peripheral iridectomy surgery, the application of pranoprofen eye drops was safe and effective, and it could reduce the risk of hormone induced ocular hypertension, it had clinical reference value.
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