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| 质子泵抑制药预防骨科手术患者应激性溃疡用药调查 |
| Investigation in the Use of PPI for Preventing the SU in Orthopaedic Surgery |
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| DOI： |
| 中文关键词: 质子泵抑制药；骨科手术 应激性溃疡；预防 合理用药 |
| 英文关键词:Proton pump inhibitor (PPI) Orthopedic surgery Stress ulcer Prevention Rational drug use |
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| 中文摘要: |
| 摘 要 目的:调查骨科手术患者使用质子泵抑制药 (PPI)预防应激性溃疡(SU)的用药情况，评价其使用合理性。方法：采用回顾性调查方法，选取我院2013年6月25日～2013年12月25日19个骨科病区手术患者出院病历1 140份，对其中PPI使用情况进行统计分析，评价使用合理性。结果： 纳入研究的 1 140名患者中有327例(28.68％)患者使用PPI进行SU的预防,145例（44.34%）有适应证，其中泮托拉唑、兰索拉唑的使用频率最高；用法用量合理19例（13.1%）；给药时机均为术后第一日，药途径均为静脉滴注，给药时机及途径均不合理。结论：我院存在过渡使用PPI预防SU的现象， 临床应掌握用药指征，防止药物滥用。 |
| 英文摘要: |
| ABSTRACT Objective:According to investigating the use of the proton pump inhibitor (PPI) for stress ulcer prevention in orthopaedic surgery, evaluated the PPI rationality in our hospital.Methods:The method of retrospective investigation in medical history was used. The patient records were randomly selected in 19 orthopaedic surgery departments of the hospital from June 25, 2013 to December 25, 2013. Statistics analysis was applied in the PPI use situation. The rationality of PPI was assessed. Results: In 1 140 patients who were brought into research, 327 patients (28.68%) using PPI into prevention of SU. 145 (44.34%) patients used PPI into prevention of SU, with medication indications, there was the highest use frequency of pantoprazole and lansoprazole; 19(13.1%) patients used PPI in rational dosage and administration; time of administration was the first day postoperation, the administration routes was intravenous drip, both use time and administration route were unreasonable. Conclusion:The overuse of PPI in preventing SU exists in clinical treatment and drug abuse should be prevented. |
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