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| 256例药物热的国内文献分析 |
| Analysis on 256 Cases of Drug Fever in Domestic Literatures |
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| DOI： |
| 中文关键词: 药品不良反应 药物热 合理用药 文献分析 |
| 英文关键词:Adverse drug reactions Drug fever Rational drug use Literature analysis |
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| 中文摘要: |
| 摘 要 目的:探讨药物热发生的机制、规律及特点，为临床合理用药提供参考。方法：通过检索中国知网(CNKI)的中国医院知识仓库(CHKD）期刊全文数据库、维普资讯网和万方数据库中公开发表的有关药物热的医药期刊文献，对检索到的符合条件文献资料进行汇总处理及统计分析。结果：发生药物热的药物以抗菌药134例（52.34%）、中药制剂36例（14.06%）、循环系统用药24例（9.38%）为主；静脉滴注占73.05%；225例患者除发热外还伴发其他症状及并发症；部分患者使用抗菌药后血常规有变化。结论：临床上要重视和正确认识药物热，加强合理用药，以降低药品不良反应风险，确保用药安全。 |
| 英文摘要: |
| ABSTRACT Objective:To explore the mechanism, regularity and characteristics of drug fever, in order to provide reference for clinical ralional medication. Methods:Chinese Hospital Knowledge Databases（CHKD）, and Wanfang database and VIP were searched with key words for case reports of drug fever， and the obtained references were collected and statistical analyzed. Results: 134 cases (52.34%) of antibiotic drugs，36 cases (14.06%) of Chinese medicine preparation and 24 cases (9.38%) of circulatory system drugs were in the drugs of drug fever based; Intravenous drip accounted for 73.05% of the highest; 225 cases were accompanied with other symptoms and complications; There were some patients had blood change after using antibiotics.Conclusion: We should correctly understand and pay attention to the drug fever clinically, strengthened the rational drug use, reduce the risk of ADR, and ensure drug safety. |
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