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依达拉奉联合常规治疗急性脑梗死疗效及对患者血清铁蛋白含量影响
Observed Efficacy of Edaravone Combined with Conventional Therapy in Acute Cerebral Infarction and Effect on Serum Ferritin Content of Patients
  
DOI:
中文关键词:  依达拉奉  脑梗死  血清铁蛋白
英文关键词:Edaravone  Cerebral infarction  Serum ferritin
基金项目:
作者单位
孙斌 台州市立医院神经内科(浙江台州 318000) 
梁海燕 台州市立医院神经内科 
陈瑛 台州市立医院神经内科 
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中文摘要:
      摘 要 目的:观察依达拉奉治疗急性脑梗死的临床疗效及对患者血清铁蛋白(SF)的影响。方法:90例脑梗死患者随机分成对照组和观察组,观察组在对照组常规治疗基础上加用依达拉奉注射液30 mg,ivd bid,连用14 d。比较两组患者治疗前后神经功能缺损评分和血清铁蛋白含量。结果:治疗后两组患者神经功能缺损评分和血清铁蛋白含量均较治疗前下降(P<0.05),且观察组均明显低于对照组(P<0.01)。结论:依达拉奉能降低脑梗死患者神经功能缺损评分和血清铁蛋白含量,促进神经功能恢复,临床疗效明显。
英文摘要:
      ABSTRACT Objective:To observe the clinical effect of edaravone in treatment of acute cerebral infarction and effect on protein of serum iron (SF). Methods: 90 cases of cerebral infarction patients divided into observation group and control group at random. On the basis of the conventional treatment, observation group was injected 30 mg infusion of edaravone daily, twice a day, QD for 14 days. Neurological function defect score and serum ferritin were compared before and after treatment. Results:The nerve function defect score and serum ferritin content in the patients of two groups were decreased compared with those before treatment (P<0.05), and observation group decreased more obviously than control group (P<0.01). Conclusion: Edaravone could reduce neurological deficit score and serum iron protein content of patients with cerebral infarction and promoted the recovery of neurological function. The clinical curative effect was obvious.
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