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| 374例高龄男性维生素D补充情况的调查 |
| Investigation to Supplement Vitamin D in 374 Men Aged 80 and Over |
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| DOI： |
| 中文关键词: 25-羟基维生素D 维生素D 男性 高龄 药物利用 |
| 英文关键词:25-hydroxyvitamin D Vitamin D Man Aged Drug utilization |
| 基金项目:浙江省医药卫生平台重点资助项目（编号：2016ZDA002）；浙江省人民医院优秀青年人员科研启动基金（编号：zry2015C002） |
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| 中文摘要: |
| 摘 要 目的:调查高龄男性血清25-羟基维生素D［25（OH）D]的正常情况，分析补充维生素D与血清25（OH）D的关系。方法：对374例高龄男性维生素D补充情况进行调查，并检测其血清25（OH）D，分析两者间的关系。 结果：374例高龄男性中，血清25（OH）D水平正常率仅为10%，其中88例（24%）补充维生素D ，其血清25（OH）D水平为（20.82±9.27） ng·ml-1，286例（76%）未补充维生素D，其25（OH）D水平为（18.27±8.49 ）ng·ml-1，差异有统计学意义（P＜0.05）。 结论：高龄男性血清维生素D正常率较低，而补充维生素D可能是提高高龄男性25（OH）D水平的重要方法。 |
| 英文摘要: |
| ABSTRACT Objective: To evaluate the status of vitamin D normality in men aged 80 and over, and to investigate the association between serum 25 hydroxyvitamin D [25(OH)D] and supplementing vitamin D. Methods:A cross sectional survey was conducted in a cohort comprising 374 men aged 80 and over. All participants underwent an questionnaire survey for supplementing vitamin D. Serum 25(OH)D measurement was conducted, and the association between serum 25(OH)D and supplementing vitamin D was analyzed. Results:Vitamin D normality［25(OH)D≥30 ng·ml-1] were found in 10% men aged 80 and over. In the 88 cases (24%) of elderly men who frequently supplement vitamin D with or without supplemental calcium, the mean serum 25(OH)D level was significantly higher than in the other elderly men [(20.82±9.27)ng·ml-1 vs (18.27±8.49) ng·ml-1, P＜0.05]. Conclusion:Vitamin D normality was too low in men aged 80 and over. To supplementing vitamin D might be an effective way to increase the level of serum 25 hydroxyvitamin D. |
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