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荆门地区2014年药品不良反应报告分析
Analysis on the Adverse Drug Reaction Reports of Jingmen Area in 2014
  
DOI:
中文关键词:  药品不良反应  报告  监测  严重的药品不良反应
英文关键词:Adverse drug reaction  Reports  Mornitor  Serious adverse drug reactions
基金项目:
作者单位
白玉 邵寅 郭晓平 王琴 王玲 ①荆门市第一人民医院药学部(湖北荆门 448000)②湖北五二五投资有限公司医院。 
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中文摘要:
      摘 要 目的:对荆门地区2014年药品不良反应(ADR)报告情况进行统计分析,并与前3年的数据进行比较,为ADR监测工作提供参考。方法:收集荆门地区2014年各单位上报国家药品不良反应监测中心的2 303份ADR报告,通过患者基本情况、报告单位、ADR类型、药品种类、结果评价等方面进行回顾性分析。同时回溯2011~2013年上报的ADR报告数据进行对比分析。结果:2 303例ADR报告中,以医疗机构的报告为主,占99.8%;静脉滴注引起的ADR占81.0%;抗感染药引起的ADR占43.7%,以头孢菌素所致ADR最多;引起免疫系统的ADR最多,占38.1%;严重ADR病例较2013年增加1.4%;市ADR中心评价结果为“很可能”的ADR最多,占72.7%;百万人口ADR的发生比例为767例。结论:重视ADR监测工作,重点关注新的严重ADR,提高医务人员对ADR的认识,提高合理用药水平,鼓励主动上报ADR并保证上报内容的准确性。
英文摘要:
      ABSTRACT Objective: To analysis on the ADR characteristics of Jingmen area in 2014. Through the comparison for the data of last 3 years, provided a reference for the ADR monitoring work. Methods:2 303 ADR reports from Jingmen area which units reported to the adverse drug reaction monitoring center were collected, the patient’s basic condition,types of ADRs,drug varieties and result evaluation were retrospective analyzed. Meanwhile, given the contrast analysis of the data reported in the 2011 to 2014. Results:In 2 303 reports, many reports were came from medical institutions(99.8%); the ADR from intravenous drip accounted for 81.0%;43.7%ADR cases were caused by anti infective agent, most caused by cephalosporin; the most of ADR caused by immune system, which was 38.1%; Severe ADR reports increased 1.4% in 2014 compared with those in 2013. The results of assessment ADR“quite possible” came from monitoring center accounted for the largest proportion(72.7%),its incidence was 767 cases per million population.Conclusion: Each unit must pay great attention to the ADR monitoring work, focus on the new and serious ADR and improve the initiative and accuracy of reports, to help medical staff raising awareness and understanding ADR, and promote clinical rational drug use.
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