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某部队医院军人病房2012~2014年口服抗高血压药应用调查
Investigation of Utilization of Oral Antihypertensive Drugs in a Military Hospital Military Ward During 2012-2014
  
DOI:
中文关键词:  抗高血压药  军人病房  药物利用
英文关键词:Antihypertensive drugs  Military ward  Drug utilization
基金项目:
作者单位
钱先中 金迪 王冬雪 孙高中 张人丹 仵利军 ①解放军第100医院药械科(江苏苏州 215007)②解放军南海舰队门诊部③解放军第100医院军人病房。 
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中文摘要:
      摘 要 目的:调查某部队医院军人病房口服抗高血压药使用情况,为提高用药合理性和药事管理水平提供参考。方法:采用回顾性分析方法,对2012~2014年某部队医院军人病房使用口服抗高血压药的品种、金额、用药频度(DDDs)、限定日费用(DDC)等进行统计分析。结果:2012~2014年某部队医院军人病房口服抗高血压药使用金额逐年增加,最低增幅达10.04%。2012~2014年金额排列前3位的均为钙通道阻滞药(CCB)、血管紧张素Ⅱ受体拮抗药(ARB)、血管紧张素转换酶抑制药(ACEI),合计占口服抗高血压药销售总金额的87.74%以上,其中,CCB的销售金额占口服抗高血压药销售总金额的40.71%以上。3年中,单品种销售金额和DDDs排列首位的均为氨氯地平;2012年和2013年DDDs前3位的药品是氨氯地平、左旋氨氯地平和缬沙坦,2014年DDDs前3位是氨氯地平、左旋氨氯地平和美托洛尔;DDC最高的均为非洛地平。结论:某部队医院军人病房口服抗高血压药整体结构合理,符合《中国高血压防治指南》(2010年版)的用药原则。疗效好、使用方便、不良反应小的抗高血压药是患者选择的主要品种。
英文摘要:
      ABSTRACT Objective:To investigate the application of oral antihypertensive drugs in a military hospital military ward, and to provide reference for improving the level of rational use of drugs and pharmacy administration. Methods:By retrospective method, the utilization of oral antihypertensive drugs in a military hospital military ward during 2012 2014 were analyzed retrospectively in respect of drug types, consumption sum, DDDs and DDC, etc. Results:The consumption sum of oral antihy pertensive drugs increased year by year in a military hospital military ward during 2012 2014, the lowest growth rate reached above 10.04%. During 2012 2014, top 3 drugs in the list of the consumption sum were calcium channel blockers(CCB), angiotensinⅡreceptor blocking agents(ARB)and angiotensin converting enzyme inhibitor(ACEI), three types of oral antihypertensive drug accounted for over 87.74%, the consumption sum of CCB accounted for over 40.71%of total . In 3 years, the first single drugs in terms of consumption amount and DDDs were amlodipine, top three drugs in the list of DDDs were levamlodipine, amlodipine and valsartan from 2012 to 2013, while amlodipine, levamlodipine and metoprolol ranked the top three in DDDs list in 2014. In terms of DDC, felodipine was the highest. Conclusion: The structure of oral antihypertensive drugs usage in a military hospital military ward was reasonable on the whole in accordance with “Chinese Guide for Prevention and Treatment of Hypertension”(2010 revised edition). Oral antihypertensive drugs with good efficacy, convenient route of administration and fewer side effects were the main varieties patients with high blood pressure selected.
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