| ABSTRACSystemic lupus erythematosus was a challenging autoimmune disease with multiorgan dysfunction induced by diverse autoantibodies, and the strategy of immunosuppressive therapy was not only the hotspot, but also the difficult viewpoint on acute critical and refractory cases in clinic. The data hint many immunosuppressive therapies, such as glucocorticoids, hydroxychloroquine, azathioprine, cyclosporine, tacrolimus, intravenous immunoglobulin, plasma exchange and biologicals, should be effective and safe during a lupus pregnancy. In the future, the multicenter studies should focus on efficacy and safety of immunosuppressive therapy during pregnancy in systemic lupus erythematosus. |
