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某院风湿免疫科成年患者25-羟维生素D水平现况调查
Epidemiologic Survey of Serum Levels of 25 Hydroxy Vitamin D in Adult Patients with Rheumatism in One Hospital
  
DOI:
中文关键词:  25羟维生素D  缺乏  流行病学调查
英文关键词:25 hydroxy vitamin D  Deficiency  Epidemiologic survey
基金项目:
作者单位
张丽华 庞丽霞 林涛 刘世铖 呼伦贝尔市人民医院 ①风湿免疫科②检验科(内蒙古呼伦贝尔021000) 
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中文摘要:
      摘 要 目的:为了解某院风湿免疫科患者的25 羟维生素D[25(OH)D]水平,以防治患者骨质疏松及其他疾病的发生。方法:调查2014年1~7月某院风湿免疫科3 331例成年患者的血清25(OH)D水平,采用电化学发光法进行检测,并对调查结果进行统计分析。结果:3 331患者中76.04%存在25(OH)D缺乏,25(OH)D充足的患者仅占10.54%。门诊与住院患者25(OH)D缺乏率差异无统计学意义(P>0.05);女性25(OH)D缺乏的比例明显高于男性(P<0.05);18~50岁年龄段的25(OH)D缺乏比例高于其他年龄(P<0.05);1~5月25(OH)D缺乏患者比例最高,6~7月有明显下降,6~7月与其他月份差异有统计学意义(P<0.05)。结论:我院风湿免疫科门诊及住院患者均普遍存在25(OH)D缺乏,间接反映我市居民25(OH)D水平不高,需及时采取措施以改善目前状况。
英文摘要:
      ABSTRACT Objective:To evaluate the nutritional status serum levels of 25 hydroxy vitamin D in adult patients with rheumatism in one hospital, in order to prevent and cure osteoporosis. Methods:A total of 3 331 in and out adult patients with rheumatism were enrolled from January to July, 2014. The serum levels of 25 hydroxy vitamin D of patient included was assayed by electrochemiluminescence immunoassay, and the survey results were statistical analyzed. Results:There were 76.04% in 3 331 patients with 25 (OH) D deficiency, 25 (OH) D sufficient accounted for only 10.54% of total. There was no statistically significant difference between outpatient and inpatient with the rate of 25 (OH) D deficiency; the 25 (OH) D deficiency in female patients were significantly higher than male (P<0.05). The highest proportion of 25 (OH) D deficiency patiens was found in 18 50 years old patients(P<0.05); The proportion of 25 (OH) D deficiency patients which examine from January to May was highest, while it decreased from June to July,and the differance had statistical significance(P<0.05). Conclusion:The 25 (OH) D deficiency of outpatient and inpatient in our hospital with rheumatism was common, which suggested the low level of 25 (OH) D in our residents. Effective measures should be carried out to improve the situations.
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