| ABSTRACT Objective:To investigate the regular pattern of ADR caused by intravenous injections and provide reference for clinical medication risk control.Methods: The ADR reports, which came from 158 network hospitals covered 2008 to 2014, was distilled from PLA ADR monitoring center and analyzed retrospectively. Results: Among the 70 672 ADR reports, 4 181 cases (5.91%) were sever and 4 382 cases (6.19%) were new. Comparing the age distribution and the Six Nationwide Population Census, there was a similar trend in the distribution curve. Of all the ADR reports, skin and appendages disorders were the most frequent ADR (26.04%), and anti infective agents were the most frequent suspected drugs (36.09%), more than half ADR (50.78%) were discovered within 30 mins after the first dose. Of all the sever ADR reports, body as a whole general disorders were the most frequent ADR (22.87%), and anti tumor drugs were the most frequent suspected drugs, the most common incubation period was about 3 days to 7days（20.88%）. Conclusion:The electronic management of ADR reports made data mining possible; the data was meaningful in sense of demography, and could indicate the trend of overall variation; rule of sever ADR occurring was unique, and should be deeper mined. |
