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| 207例药源性过敏性休克分析 |
| Analysis of 207 Reports of Drug induced Anaphylactic Shock |
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| DOI： |
| 中文关键词: 药品不良反应 过敏性休克 回顾性分析 |
| 英文关键词:Adverse drug reaction Anaphylactic shock Retrospective analysis |
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| 中文摘要: |
| 摘 要 目的： 分析药源性过敏性休克发生的一般规律及抢救措施，为临床安全用药提供参考。方法：对阜阳市药品不良反应监测中心2011～2014年收到的207例过敏性休克病例报告，按照患者性别、年龄、过敏性休克发生时间、给药途径、怀疑药品、抢救药物和过敏性休克转归等情况进行回顾性分析。结果：导致过敏性休克的可疑药物中，抗微生物药、中药注射剂、血液系统药构成比居前3位；静脉用药所占比例最高（91.3％）；过敏性休克大多数发生在用药后20 min内，占84.5％。结论：临床应重视药源性过敏性休克的发生，用药前询问过敏史，严格掌握用药指征，注意用药全程的监护，一旦出现不良反应及时停药，并采取适当措施予以对症抢救治疗。 |
| 英文摘要: |
| ABSTRACT Objective:To analyze the general regularity and rescue measures of the drug induced anaphylactic shock，provide references for clinical safe use of medicine．Methods:207 reports of anaphylactic shock in Fuyang center for food medical devices adverse drug reaction/events monitoring from 2011 to 2014,were retrospective analyzed in terms of genders and ages, shock time, route of medication, suspected drug, first aid drugs, and anaphylactic shock outcome．Results:Anti microbial drugs，Traditional Chinese Medicine injections and blood system drugs were the top three position．The constituent ratio of intravenous drug was the highest，accounting for 91.3%．The majority of anaphylactic shock occurred within 20 minutes after administration，accounting for 84.5%. Conclusion:The clinical should pay attention to drug induced anaphylactic shock，strict indications medication，strengthen the guardianship medication． |
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