| ABSTRACT Objective:Analyze 964 reported adverse drug reactions (ADRs), so as to improve the security of clinical drug application. Methods:964 ADRs from 2013 to 2015 in our hospital were collected, made comprehensive analysis such as the cases age groups, impaired parts and systems, drug varieties, the proportion of severe ADR (SADR) and so on.Results: Anti infection agents took 7 places of the top 10 drugs causing ADR. Main presentations of the ADRs were lesion of skin and its appendages (415 cases,43%),damage of gastrointestinal system (216 cases, 22.4%), systemic lesion (19.3%), damage of respiratory system (5.7%), damage of central and peripheral nervous system (4.1%), damage of cardiovascular system (2.1%). The proportion of SADRs (38 cases) was 3.94%.Conclusion:Medical institutions must strengthen the monitoring of ADR. Adverse reactions (especially never occurred before) should be reported as soon as possible, to ensure the security of drug application. |
