| ABSTRACT Objective:Adopting adverse drug reaction(ADR) signal detection method to find out the ADR signals of antibacterial agents.Methods:To detect the signals of top 5 antibacterial drugs by adopting MHRA (medicines and healthcare products regulatory agency) comprehensive standard measures was to excavate ADR signals. Results:Eight signals have been tested through ADR signal detection: cefpiramide rash erythematous, cefpiramide rash, levofloxacin nausea, levofloxacin abdomina pain, cefodizime anaphylactoid reaction, piperacillin anaphylactic shock, piperacillin rash, and ceftriaxone pruritus.Conclusion:The ADR signals of antibacterial agents validated that there was a certain degree of correlation between the drug and the adverse reactions, which reminded the safety of drug, and provided reference for using drug rationally. |
