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| 2010～2015年浙江省11家医院肺癌患者5-HT3受体拮抗药应用分析 |
| Application Analysis of 5-HT3 Receptor Antagonists Used for Lung Cancer in 11 Hospitals of Zhejiang from 2010 to 2015 |
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| DOI： |
| 中文关键词: 5-HT3受体拮抗药 肺癌 用药金额 用药频度 限定日费用 药物利用 |
| 英文关键词:5-HT3 receptor antagonists Lung cancer Daily costs DDDs DDC Drug utilization |
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| 中文摘要: |
| 摘 要 目的：了解2010～2015年浙江省11家医院肺癌患者5-HT3受体拮抗药的应用情况和趋势，促进其合理用药。方法：抽取2010～2015年浙江省11家医院肺癌患者的医嘱用药数据，对其用药金额、用药频度（DDDs）、限定日费用（DDC）进行回顾性分析。结果：2010～2015年，浙江省11家医院肺癌患者使用5-HT3受体拮抗药的用药金额逐年上升，但在总金额中的占比呈下降趋势，而2015年5-HT3受体拮抗药不论用药金额还是占总用药金额比例都有所升高。6年内使用金额比例排名首位的分别为托烷司琼（2010～2014年）和帕洛诺司琼（2015年）。5-HT3受体拮抗药DDDs排名首位是托烷司琼（2010～2015年），DDC排名首位为帕洛诺司琼。结论：浙江省11家医院肺癌患者使用的5-HT3受体拮抗药基本合理，安全有效、经济方便的5-HT3受体拮抗药在临床使用中占优势。 |
| 英文摘要: |
| ABSTRACT Objective:To investigate the utilization, characteristic and tendency of 5-HT3 receptor antagonists used by lung cancer patients and to provide reference resources.Methods:Regard to consumption sum, DDDs, and DDC, the collected prescriptions data of 5-HT3 receptor antagonists used by lung cancer patients in 11 hospitals of Zhejiang during 2010 2015 were analyzed by the retrospective research method. Results:The consumption sum of 5-HT3 receptor antagonists increased from 2010 to 2015. The top 5-HT3 receptor antagonists of the consumption sum were tropisetron (2010 2014) and palonosetron (2015), the top of DDDs were tropisetron, and palonosetron (2010 2015) took the first three drugs in DDC. Conclusion:The applications of 5-HT3 receptor antagonists used by lung cancer patients were basically reasonable in 11 hospitals of Zhejiang, and those drugs which were of rational, safe, effective and valid predominated in clinical application. |
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