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| 476例药品不良反应报告分析 |
| Analysis of 476 Cases of Adverse Drug Reaction Reports |
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| DOI： |
| 中文关键词: 药品不良反应 监测 报告 安全用药 |
| 英文关键词:Adverse drug reaction Monitoring Report Safe medication |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：分析某三甲医院2015年药品不良反应(ADR)发生的特点和规律，促进临床安全用药。方法：采用回顾性调查方法,对该院2015年上报的476例有效ADR报告，按照患者性别、年龄、给药途径、药品种类、涉及的器官或系统及其临床表现等进行统计分析。结果：476例ADR报告中，年龄分段在0～10岁的婴幼儿患者 ADR构成比较高，占49.16%;静脉给药导致ADR占87.39%；ADR构成比最高的为抗感染药，占66.15%，其次为中药制剂，占10.12％；临床表现以皮肤及其附件损害最为常见，占60.81%。结论：医务人员应重视 ADR的监测与报告,促进临床合理用药,保障患者用药安全。 |
| 英文摘要: |
| ABSTRACT Objective:To analyze the characteristics and regularity of adverse drug reaction(ADR) occurred in the second affiliated hospital of Nanjing Medical University in 2015, to offer some information about rational drug use and make the drug use more rationally. Methods:476 effective ADR case report collected in our hospital by doctors and pharmacists were analyzed statistically in respect of patients’ age and sex, route of administration, category of drug, organs and systems involved, and the clinical manifestation of the ADR. Results: Among 476 ADR cases, the children under the age of 10 years accounted for 49.16%, 87.39% were induced by intravenous dripping injection. The main clinical manifestations of ADR were lesions of skin and its appendages in 60.81%, 66.15% were induced by anti infective drugs. Conclusion:It was important to strengthen ADR monitoring and ensure safe medication. |
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