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复方樟脑乳膏治疗局限性神经皮炎疗效观察
Clinical Observtion of Compound Camphor Cream in the Treatment of Localized Neurodermatitis
  
DOI:
中文关键词:  神经性皮炎  复方樟脑乳膏  丹皮酚软膏
英文关键词:Neurodermatitis  Compound camphor cream  Paeonol cream
基金项目:
作者单位
刘随高琳刘斌徐倩倩 ①湖北医药学院附属随州医院皮肤科 随州市中心医院皮肤科(湖北随州 441300) 
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中文摘要:
      摘 要 目的:评价复方樟脑乳膏治疗局限性神经性皮炎的疗效和安全性。方法:90例局限性神经性皮炎患者随机分为观察组和对照组各45例。观察组外涂复方樟脑乳膏bid,对照组外涂丹皮酚软膏bid。14 d后比较两组临床有效率,治疗前后瘙痒积分及体征积分变化,以及药品不良反应。结果:观察组和对照组有效率分别为87.7%vs.62.2%,差异有统计学意义(P<0.05)。治疗后,两组瘙痒积分及体征积分均较前有明显改善(P<0.05),且观察组均明显优于对照组(P<0.05)。两组药品不良反应发生率比较,差异无统计学意义(P>0.05)。结论:复方樟脑乳膏治疗局限性神经皮炎疗效优于丹皮酚乳膏,且安全性较好。
英文摘要:
      ABSTRACT Objective:To evaluate the efficacy and safety of the compound ceamphor cream on treating localized neurodermatitis.Methods:90 patients with localized neurodermatitis were randomly divided into observation group (45 case) and control group (45 case). The observation group were given compound camphor cream, twice per day; the control group were given paeonol cream, twice per day. After 14 days’s treatment, the clinical efficiency, itching points, signs of integration and adverse reaction of two groups were compared. Results:The clinical efficacy of the observation group and control group was 87.7%and 62.2% respectively, there were significant differences between the two groups(P<0.05). After treatment, the itching points and signs of integration of both two groups were improved(P<0.05), and the observation group had statistical significance than the control group(P<0.05). The adverse reactions of the two groups had no significant difference(P>0.05). Conclusion:The curative effect of compound camphor cream in the treatment of neurodermatitis was better than that of paeonol cream, and it had good safety.
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