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| 银杏叶提取物联合常规治疗老年急性脑梗死疗效观察 |
| Observation on Effectiveness of Ginkgo Biloba Extract Combined with Conventional Therapy for the Patients with Acute Cerebral Infarction in the Elderly |
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| DOI： |
| 中文关键词: 银杏叶提取物 脑梗死，急性 老年患者 |
| 英文关键词:Ginkgo biloba extract Acute cerebral infarction Eldly patients |
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| 中文摘要: |
| 摘 要 目的：探讨银杏叶提取物联合常规治疗老年急性脑梗死的临床疗效。方法：老年急性脑梗死患者65例随机分为观察组和对照组。对照组患者给予常规治疗；观察组患者在此基础上加用银杏叶提取物。两组疗程均为3周。采用神经功能缺损评分（NHISS）评定两组疗效；比较两组患者治疗前后简易智力状态检查量表(MMSE)、日常生活能力量表(ADL)、凝血功能及血流动力学指标变化。结果：观察组总有效率为84.85％，明显高于对照组的62.50％ (P＜0.05)。治疗后，两组MMSE评分和ADL评分值均较前明显提高(P＜0.05)，且观察组两项评分均优于对照组(P＜0.05)。治疗后，两组凝血功能与血液流变学各项指标均较前明显改善(P＜0.05)，且观察组各项指标均优于对照组(P＜0.05)。结论：银杏叶提取物治疗老年性急性脑梗死疗效更显著，不良反应少，值得在临床中推广。 |
| 英文摘要: |
| ABSTRACT Objective:To investigate the clinical effects of ginkgo biloba extract combined with conventional therapy for the patients with acute cerebral infarction in the elderly. Methods:65 patients with acute cerebral infarction were randomly divided into observation group and control group. All cases received conventional therapy. On the basis, observation group of patients added ginkgo biloba extract. The courses of treatment of two groups were 3 weeks. The efficacy were evaluated by using national institute of health stroke scale(NIHSS); and the mini mental state examination(MMSE)， activities of daily living(ADL)，testing blood coagulation function and hemodynamic index changes of the two groups before and after treatment were compared. Results:The effective rate of observation group was 84.85%, obviously higer than control group’s 71.88%(P＜0.05). There were significant improvements of MMSE and ADL total scores in both two groups after treatment (P＜0.05), and the observation group was better than the control group(P＜0.05). The vein blood coagulation function and hemodynamic index in both two groups were improved than before(P＜0.05), while the indicators of observation group were significant superior to the control group(P＜0.05). Conclusion:The therapy with ginkgo biloba extract had positive effect and cause less adverse reaction for the patients with acute cerebral Infarction in the elderly. It was worth popularizing in clinic. |
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