| ABSTRACT Objective:To study the clinical curative effects of using sodium hyaluronate eye drops combined with recombinant human epidermal growth factor (rhEGF) eyedrops treating for dry eyes after cataract surgery. Methods:From January 2015 to June 2016 year in our hospital 80 patients (80 eyes) with dry eyes secondary to cataract surgery were selected and randomly divided into the observation group and the control group (40 cases in each group); The control group were given sodium hyaluronate eye drops for treatment, while the observation group had rhEGF eyedrops on basis of the control group treatment; All the two groups were treated for 4 weeks. In the two groups before treatment, 2 weeks and 4 weeks after treatment dry eye symptoms, tear break up time (BUT), Schirmer test (SIt), corneal fluorescein staining (FL), and adverse drug reaction(ADR) were recorded and compared. Results:The total efficiency (97.5%) in the observation group was significantly higher than that in the control group (75%,P<0.05). 2 weeks and 4 weeks after treatment, the dry eye symptom scores of two groups were all significantly decreased (P<0.05), but those of the observation group decreased more significantly (P<0.05). After treatment, BUT and SIt of two groups were all increased significantly compared with before treatment, and FL was significantly lower than before treatment, but BUT and SIt of the observation group increased more significantly (P<0.05), while FL decreased significantly (P<0.05). The incidence of ADR in the control group was significantly higher than that in the observation group (P<0.05). Conclusion:Using sodium hyaluronate eye drops combined with rhEGF eyedrops to treat dry eyes after cataract surgery can significantly improve clinical symptoms, promote the stability of the tear film, and reduce tear secretion and corneal injury, worthy of clinical promotion. |
