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| 2012～2017年我州土家族及汉族患者药品不良反应分析 |
| Analysis of Adverse Drug Reactions of Tujia and Han Patients in 2012-2017 |
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| DOI： |
| 中文关键词: 药品不良反应 土家族 抗菌药物 给药途径 安全用药 |
| 英文关键词:Adverse drug reactions Tujia population Antibacterial agents Route of administration Drug use safety |
| 基金项目: |
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| 中文摘要: |
| 摘 要 目的：探讨恩施地区药品不良反应发生特点及土家族与汉族发生抗菌药物不良反应（ADR）的差异。方法：选取2012年1月～2017年7月恩施地区上报的ADR报告，从患者一般情况、ADR严重程度及发生时间、β 内酰胺类ADR、给药途径及ADR转归等方面，比较土家族及汉族患者发生的ADR的差异。结果：土家族与汉族患者发生的ADR，在β 内酰胺类尤其是头孢菌素类药物所致ADR分布、口服与静脉滴注用药分布，以及ADR转归情况等方面的差异有统计学意义（P<0.01）。两者发生ADR严重程度无差异（P﹥0.05）。结论：ADR的发生存在种族差异，少数民族地区在使用抗菌药物及给药途径方面应关注民族差异，减少ADR发生。 |
| 英文摘要: |
| ABSTRACT Objective:To investigate the occurrence characteristics of adverse drug reactions (ADR) in Enshi region and the difference of adverse drug reactions between the Tujia and the Han population. Methods:All ADR reported in Enshi from January 2012 to July 2017 July were chosen and analyzed. The general situation of patients, severity of ADR and time of occurrence, ADR of β lactams, drug delivery pathway and ADR of outcome were analyzed. The differences between Tujia and Han in the above items were analyzed. Results: The ADR in Tujia and Han people, caused by β lactams, especially cephalosporin, there were significant differences between them in distribution, oral and intravenous, and the ADR of outcome (P<0.01). There was no difference in the severity of ADR (P﹥0.05). Conclusion:There were ethnic differences in the occurrence of ADR. Minority areas should pay attention to ethnic differences in the use of antibacterial agents and routes of administration, and reduce the incidence of adverse drug reactions. |
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