| ABSTRACT Objective:To evaluate the utilization of immunoregulatory drugs in 35 hospitals in Nanjing area, and provide a clinical reference for the rational use of drugs. Methods:According to the sales data of immunoregulatory drugs in 35 hospitals in Nanjing area from 2014 2016, the utilization of immunoregulatory drugs was analyzed retrospectively in respect of consumption sum, DDDs and DDC, by using amount analysis and drug frequency analysis.Results: The top 3 immunosuppressive drugs in the list of consumption sum were tacrolimus, mycophenolate mofetil and CsA. In terms of DDDs, tripterygioside and tacrolimus, mycophenolate mofetil ranked top 3. The consumption sum and DDDs of immunosuppressive drugs increased year by year in Nanjing area. The ratio of serial number of consumption sum and DDDs was from 0.5 to 4.0. The top 3 immunopotentiating drugs in the list of consumption sum were interleukin, ulinastatin and pidomoder. In terms of DDDs, interleukin and sodium carboxymethyl starch, pidomoder ranked top 3. The consumption sum and DDDs of immunosuppressive drugs was fluctuating. The ratio of serial number of consumption sum and DDDs was from 0.3 to 2.0.Conclusion:The application of immunomodulatory drugs in nanjing was basically in line with the current trend of patient’s need. The treatment should be taken according to the characteristics of the drug and the actual situation of the patients to avoid the abuse. To ensure the safe, effective and economic basic principles of clinical drug use. |
