ABSTRACT Objective:To observe the real world clinical applications and safety of Tanreqing injection. Methods:100 inpatients of Nanjing Jiangning District Hospital of Chinese Medicine treated with Tanreqing injection were observed during August to November 2014. The overall condition of patients, diagnosis, drug application, safety and drug utilization were analyzed. Results:Clinical use of Tanreqing injection was for the treatment of respiratory disease, such as pneumonia, acute exacerbation of chronic bronchitis, acute bronchitis. The common TCM syndrome was Phlegm heat obstructing lung. The clinical application of Tanreqing injection has following problems, including use beyond TCM syndrome, high concentration of drug, infusion tube didn’t washed between drugs, dripping too fast, too much drug combination, which were irrational according to the drug instructions. Adverse drug reaction (ADR) did not occur in the research. Over dose occurred according to drug utilization research. Conclusion: Tanreqing injection did not used correctly according to the drug instructions in Nanjing Jiangning District Hospital of Chinese Medicine, which increased the risk of ADR. Management measures should be taken to correct the clinical application of Tanreqing injection and guarantee the safety for patients. |