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| 我院门诊2013～2015年抗骨质疏松类药物利用分析 |
| Analysis of Anti osteoporosis Drugs Application from 2013 to 2015 in the Outpatient Department of A Hospital |
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| DOI： |
| 中文关键词: 抗骨质疏松药物 用药频度 限定日费用 药物利用 |
| 英文关键词:Anti osteoporosis drugs DDDs DDC Drug utilization |
| 基金项目:上海市临床药学重点专科建设项目（编号：2016-40044-002） |
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| 中文摘要: |
| 摘 要 目的：调查分析2013～2015年我院门诊药房抗骨质疏松类药物利用情况，为临床合理用药提供参考。方法：将2013～2015年我院门诊使用的骨质疏松药物分为五大类，分别统计各类别的销售金额及构成比。采用限定日剂量（DDD）法，对门诊使用的19种抗骨质疏松药物的用药频度（DDDs）、限定日费用（DDC）、药品金额与DDDs序号比（K）进行统计分析。结果：2013～2015年我院抗骨质疏松药物的销售金额呈先下降再上升的趋势，相比于2013年，2015年的销售金额增长了17.10%。3年中活性维生素D都是总金额占比最高的类别，而降钙素类药物的销售金额占比逐年增加。DDDs排名第一的药品始终为我院自产的氨基酸钙片。DDC值最高的为鲑鱼降钙素喷鼻剂（金尔力），最低的为碳酸钙D3片(Ⅱ)（朗迪）。大多数药品的K值接近于1。结论：2013～2015年我院抗骨质疏松药物使用基本合理。 |
| 英文摘要: |
| ABSTRACT Objective: Analyze the application of anti osteoporosis drugs from 2013 to 2015 in the out patient department of our hospital, to provide reference to clinical application. Methods:Anti osteoporosis were classified into five groups, according to their pharmacological effects. Then, sale amounts and the percentage of total sales were calculated by groups. Defined daily doses (DDDs), defined daily cost (DDC), and K values of 19 anti osteoporosis drugs applied in the out patient department were further detected. Results: Sale amounts of anti osteoporosis drugs fluctuated in 2013 to 2015, but the sale amounts of 2015 increased 17.10%, compared with that of 2013. Activated vitamin D occupied the largest part of sale amounts in the observed three years, the proportion of calcitonin(CT) sale amounts increased year by year. The DDDs of our hospital made preparation amino acid calcium was far exceeded other anti osteoporosis drugs. The DDC of salcatonin nasal spray was the highest,while calcium carbonate and vitamin D3 tablets(Ⅱ)was the lowest. Most investigated drugs’ K values were approaching 1, which reveals the synchronization of sale amounts and drug doses. Conclusion:Application of anti osteoporosis drugs is rational in the out patient department of our hospital from 2013 to 2015. |
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