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| 600例儿童Ⅰ类切口围手术期预防应用抗菌药物调查 |
| Investigation and Analysis on Prophylactic Utilization of Antimicrobials in Type Ⅰ Incision on 600 Children Cases |
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| DOI： |
| 中文关键词: Ⅰ类切口 抗菌药物 儿童 围手术期 预防用药 |
| 英文关键词:TypeⅠincision Antimicrobials Children Perioperative period Preventive application |
| 基金项目:上海市卫生计生系统重要薄弱学科建设项目（编号：2016ZB0305）；中国-世卫组织2016 2017双年度合作项目（编号：2016/647672-0） |
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| 中文摘要: |
| 摘 要 目的：了解住院患儿清洁手术抗菌药物的预防使用情况，为规范抗菌药物的使用提供依据。方法：采用系统随机抽样的方法随机抽取2017年1～6月出院的600例Ⅰ类切口手术患儿，回顾性统计分析患者一般情况、手术类型与抗菌药物预防使用信息，评价抗菌药物预防使用合理性。结果：600例患儿抗菌药物使用率为40.7% ，术后给药时间＞48 h占54.3%，预防用药时机不合理为9.1%，预防用药给药剂量不合理为28.1%，预防使用抗菌药物的手术主要是涉及重要脏器如脑、脊髓及心脏等手术，但也有部分其他清洁手术预防使用抗菌药物。结论：儿童Ⅰ类切口手术围手术期预防性使用抗菌药的用药指征、给药时机、持续用药时间等存在不合理现象，表现为无指征用药、预防用药使用率偏高、抗菌药物选择不合理、首次给药时机不合理、术后用药持续时间过长等，提示Ⅰ类切口手术围手术期预防性使用抗菌药物仍有待进一步规范。 |
| 英文摘要: |
| ABSTRACT Objective:To understand the application status and the rationality of antimicrobials during perioperative period in type Ⅰ incision operation so as to provide evidence for standardizing the use of antibiotics. Methods:A total of 600 perioperative cases of type Ⅰ incision operation in our hospital from January 2017 to June 2017 were selected randomly, the patients’ general conditions, surgery, and the information of antibacterial drugs prevention use were analyzed and calculated retrospectively. The rationality of antibacterial drug prevention was evaluated.Results:The use rate of antimicrobials was 40.7%, the prophylactic medication without indication accounted for 21.4%. The irrationality of the initial administration time of prophylactic antimicrobials was 9.1% and irrationality of postoperative medication time of antimicrobials was 54.3%. 〖WTHZ〗Conclusion:〖WTBZ〗The use indications of antibacterials, medication timing and medication duration remained unreasonable, which were manifested as using antimicrobial with no indications, the high use rate of prophylactic antibacterials, the unreasonable selection of antibacterial types, unreasonable timing for the first dose of medication and long duration of antibacterial use after surgery, suggesting that the perioperative prophylactic antibacterial use in type I incision surgery still remains to be further standardized. |
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