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某院住院患者中药注射剂临床应用的药物相关问题调查
Study for Drug related Problems of Traditional Chinese Medicine Injections in Clinical Application of Inpatients
  
DOI:
中文关键词:  中药注射剂  药物相关问题  合理用药
英文关键词:Traditional Chinese medicine injections  Drug related problems  Rational drug use
基金项目:安徽省蚌埠市科技发展指导性项目(编号:20160322)
作者单位
程军 汪龙 朱玲娜 蚌埠市第三人民医院药学部 安徽蚌埠 233099 
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中文摘要:
      摘 要 目的:调查中药注射剂临床应用的药物相关问题(DRPs),促进临床合理用药。方法:参考西班牙药物相关问题的研究方法Granada Ⅱ分类法及《中药注射剂临床使用基本原则》制定中药注射剂临床应用的药物相关问题分类标准,收集某院2017年1月出院患者中使用中药注射剂的全部病例855份并进行调查。结果:855份病例中有608份病例发生DRPs(71.1%),累计发生851 DRPs药次,包括225 DRP2药次,50 DRP4药次,496 DRP5药次,80 DRP6药次。DRP5发生药次最多,主要表现为溶媒选择不合理、溶媒量过少等。DRPs涉及23种中药注射剂,其中红花注射液及灯盏花素注射液位居DRPs前2位。结论:采用中药注射剂临床应用的药物相关问题分类标准来分析中药注射剂合理用药性是可行的,应制定干预措施,规范中药注射剂的合理使用。
英文摘要:
      ABSTRACT Objective:To study drug related problems of traditional Chinese medicine injections in clinical application of inpatients and to provide reference for clinical medicination. Methods: Classification criteria of drug related problems of traditional Chinese medicine injections in clinical application was established with reference to drug related problems of the Spanish Granada Ⅱ Classification and Basic principles for clinical of traditional Chinese medicine injections, and was used to study the relevant 855 cases of illness that using traditional Chinese medicine injections during 2017 January in one hospital. Results: Among the 855 patients, the total number of DRPs was 608 (account for 71.1%). Traditional Chinese medicine injections accumulated generating 851 DRPs, including 225 DRP2, 50 DRP4, 496 DRP5, 80 DRP6. The DRP5 occured most frequently. The main manifestations were unreasonable choice of solvent, too little quantity of solvent, etc. DRPs involed 23 kinds of traditional Chinese medicine injections, the safflor injection and breviscapine injection ranked top 2. Conclusion:It was reasonable and feasible to analyzing rationality of medication of traditional Chinese medicine injection according to classification criteria of drug related problems of traditional Chinese medicine injections in clinical application. It was necessary to develop intervention measure to enhance rationality of traditional Chinese medicine injections in clinical application.
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