| ABSTRACT Objective: To gain an in depth understanding of the research profile of adverse reaction signals and to objectively reflect the scientific capabilities and influence of relevant countries, institutions, and scientists in the field of studying adverse drug reactions.Methods:Using the Science Citation Index (SCI) database Web of Science as a search platform, advanced search using “adverse reaction signal mining” “adverse reaction data mining” as the subject heading, and using bibliometric methods to analyze adverse reaction signal mining as Topics related to the top 10 in terms of country/region, institution, source of authorship, publication, annual text volume, annual citation volume, and quotation.At the same time, using the Chinese Journal Full text Database in CNKI as a search platform, advanced search “adverse reaction signal mining” “adverse reaction data mining” as the subject of all Chinese literature and literature metrology analysis. The time span is from January 1st, 1990 to June 30th, 2018. Results:191 English documents were retrieved from the Web of Science database. The number of annual and year citations was the highest in 2013, the h index was 36, and 103 articles were published in the United States and France, accounting for 53.93% of the total. The number of Chinese documents retrieved in CNKI was 41, and the most studied was the Second Military Medical University. The number of documents issued was 11 and accounted for 26.83% of the total. Conclusion: The research on adverse drug reaction signal mining research increased rapidly, and has always maintained a certain degree of research interest, but the mining technology and data utilization needs to be further matured. |
