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我院老年肿瘤患者中药注射剂超说明书用药调查
Investigation of Off label Drug Use in Traditional Chinese Medicine Injections for Elderly Cancer Patients in Our Hospital
  
DOI:
中文关键词:  老年肿瘤患者  中药注射剂  超说明书用药  合理用药
英文关键词:Elderly patients with cancer  Traditional Chinese medicine injection  Off lable drug use  Rational drug use
基金项目:
作者单位
李岩 张四喜 张杰 张永凯 吉林大学第一医院 长春130021 
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中文摘要:
      摘 要 目的:了解我院老年肿瘤患者使用中药注射剂的超说明书用药情况。方法:抽取我院2015年1月~2017年7月使用中药注射剂的老年肿瘤患者病历730份,根据药品说明书及相关文献筛选出超说明书用药,分别从不同科室,不同药品,不同疾病,不同超说明书类型等方面进行数据统计,分析超说明书用药情况。 结果:730份病历,共1 175条用药医嘱,涉及12种中药注射剂;其中超说明书用药病历290份,占总病历数的39.73%;超说明书用药医嘱条数376条,占总医嘱条数的32.00%,涉及超说明书用药药品10种。超说明书医嘱数列前3位的中药注射剂为舒肝宁注射液、注射用丹参多酚酸盐、丹红注射液;注射用丹参多酚酸盐、大株红景天注射液、注射用益气复脉等3中中药注射剂超说明书医嘱的比例达到100%。超说明书类型排名前3位的是超溶媒类型、超适应证、超疗程用药;超说明书用药以肺癌患者例数最多,其次是肝癌、结肠癌。结论:我院老年肿瘤患者中药注射剂超说明书用药现象普遍存在,应加强超说明书用药管理,规范合理使用。
英文摘要:
      ABSTRACT Objective: To understand the off label drug use of Chinese traditional medicine injection in elderly tumor patients in our hospital. Methods:From January 2015 to July 2017, 730 cases of senile tumor patients who were treated with traditional Chinese medicine injection were selected. According to the drug instructions and related literature screening out the off label drugs, the statistics were carried out from different departments, different drugs, different diseases, different types of off lable and other aspects respectively. Results:There were 1 175 medical orders in 730 medical records,involving 12 kinds of traditional Chinese medicine injections, 290 medical records of overstatement, accounting for 39.73% of the total medical records. The number of prescriptions was 376, accounting for 32.00% of the total number of prescriptions, involving 10 kinds of drugs. Shuganning injection was the first three Chinese medicine injectors in the order of superscript. Salvia miltiorrhiza polyphenolic acid and Danhong injection were used for injection. The proportion of salvia miltiorrhiza polyphenolic acid injection, Hongjingtian injection and Yiqi Fumai injection were 100%. Super specification type ranking the first three were supersolute type, superindications and overtherapy, and the majority of patients were lung cancer patients, followed by liver cancer and colon cancer. Conclusion: The phenomenon of Chinese traditional medicine injection off lable drug use was common in the elderly tumor patients in our hospital, we should strengthen the management and make standard and reasonable of off lable drug use.
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