ABSTRACT Objective: To investigate the detections and drug resistances of the department of the critical care medicine in our hospital, so as to provide reference for treatment. Methods:The detections and drug susceptibility results of bacteria from the patients who had been admitted to the department of critical care medicine in our hospital between January 2015 and December 2017 were analyzed. Results:A total of 1 399 strains of bacteria were isolated durning the past three years, including 1 021 strains of gram negative bacteria (72.98%), 378 of gram positive bacteria (27.02%), among which, 448 strains of multidrug resistant organisms (MDROs) were isolated. Acinetobacter baumannii counted for the first place among the isolated bacteria (25.16%), and the antibiotic resistance rates to the carbapenems became higher and higher. The prevalence of Klebsiella pneumoniae (17.30%) counted for the second place and keep increasing durning the past three years, but the resistance to enzyme inhibitor complex and carbapenems keep climbing. Pseudomonas aeruginosa run for the third place, but the isolated rates keep decreasing in the past three years. The coagulase negative staphylococcus (CoNS), staphylococcus aureus and streptococcus pneumoniae were the first three bacteria isolated during the past three years while the isolated rates of streptococcus pneumoniae keep increasing. All of three had a serious resistance to penicillin (>90%) but no resistant stain to vancomycin, teicoplanin and linezolid was isolated. Conclusion:In the clinical work, we should choose a rational antimicrobial agent according to the bacteria distribution and drug resistance of the area. |