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1例社区获得性肺炎合并心功能、肝功能不全患者的病例分析
Case Analysis of A Patient with Community Acquired Pneumonia Combined with Cardiac and Hepatic Insufficiency
  
DOI:
中文关键词:  社区获得性肺炎  心功能不全  异甘草酸镁  溶媒  药学监护
英文关键词:Community acquired pneumonia  Cardiac insufficiency  Isoglycyrrhizinate  Menstruum  Pharmaceutical care
基金项目:上海市卫生计生系统重要薄弱学科建设项目(编号:2016ZB0304)
作者单位
乐可佳1 叶晓芬2 1.上海交通大学医学院附属仁济医院药剂科 上海 2001272.复旦大学附属中山医院药剂科 
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中文摘要:
      摘 要1例61岁男性因社区获得性肺炎、呼吸衰竭入院,治疗期间出现肝功能异常和心功能不全,丙氨酸氨基转移酶(ALT)最高为733 U·L-1,脑利钠肽(BNP)最高升至1 153 pg·ml-1。在调整患者抗感染方案的同时,临床药师建议停用异甘草酸镁,换用还原型谷胱甘肽,调整静脉药物溶媒,减少液体和钠盐入量。治疗方案调整后,患者肝功能和心功能逐步好转,7 d后复查ALT、BNP基本恢复至正常范围。
英文摘要:
      ABSTRACTA 61 old male patient with community acquired pneumonia (CAP) and type I respiratory failure was occurred cardiac and hepatic insufficiency. His alanine aminotransferase (ALT) was 733 U·L-1 and B type natriuretic peptide (BNP) was 1 153 pg·ml-1. Clinical pharmacists suggested to stop magnesium isoglycyrrhizinate and optmize the solvent to limit the fluid and sodium salt intake while the antimicrobial treatments were adjusted. The cardiac and hepatic function of the patient was getting better after adjustment. Seven days later, the ALT and BNP recovered to normal largely.
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