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2015~2017年我院住院患者皮肤药物不良反应报告分析
Analysis of Adverse Drug Reactions of Skin in Inpatients in Our Hospital during 2015-2017
  
DOI:
中文关键词:  皮肤  药品不良反应  住院患者  安全用药
英文关键词:Skin  Adverse drug reactions  Inpatients  Safe medincation
基金项目:山东省医药卫生科技发展计划项目(编号:2017WS473);山东省中医药科技发展计划项目(编号:2017-284)
作者单位
郑磊 徐洪玉 管玉瑶 杨静 宋超 山东省立第三医院 济南 250031 
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中文摘要:
      摘 要 目的:分析我院皮肤药物反应的药品种类及其发生的相关因素,促进临床早诊断和及时处理。方法:对我院2015~2017年收集的352例药物致皮肤不良反应病例报告的类型、患者年龄分布、临床表现及涉及药物、严重不良反应情况等进行统计分析。 结果:352例皮肤不良反应病例涉及的药物共有130种,其中抗菌药物居首位,给药途径以静脉滴注为主。一般的不良反应294例,严重的不良反应47例,新的不良反应11例。结论:临床医生应关注严重皮肤药物反应表现与危险因素,减少药源性不良反应的发生。
英文摘要:
      ABSTRACT Objective: To analyze the drug related factors about the occurrence of drug reactions in the skin, and promote early diagnosis and timely treatment in our hospital. Methods: The types, age distribution, clinical manifestations, drug involved and severe adverse reactions of 352 cases of skin adverse reactions in our hospital from 2015 to 2017 were analyzed. Results:352 cases of drug induced adverse skin reactions involving a total of 130 kinds of drugs, including antibiotics in the first place, the main route of administration by intravenous infusion, which contains 294 cases of general adverse reactions, 47 cases of serious adverse reactions, and 11 cases of new adverse reactions. Conclusion:Clinicians should pay attention to the manifestations and risk factors of severe skin drug reactions, to reduce the occurrence of drug induced adverse reactions.
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