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单中心耳鼻喉科门诊患者抗菌药物使用现状横断面调查
A Single Center Cross Section Investigation of Antibiotic Drug Utilization in Otolaryngology Outpatients Department
  
DOI:
中文关键词:  抗菌药物  耳鼻喉科  处方  单中心  合理用药
英文关键词:Antibiotics  Otolaryngology  Prescription  On site investigation  Rational drug use
基金项目:上海市药学会科研启动基金(编号:2007YY02010)
作者单位
闫晶超 沈剑文 陈念祖 复旦大学附属眼耳鼻喉科医院药剂科 上海 200031 
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中文摘要:
      摘 要 目的:了解耳鼻喉科门诊抗菌药物的使用现状,为同类专科间的比较及管理决策提供依据。方法:采用横断面调查的方法,调查1个月耳鼻喉科门诊处方给药途径分布情况,品种选择情况,全身使用抗菌药物消耗情况、疗程分布情况,以及克拉霉素片的用法及疗程分布情况。 结果:耳鼻喉科门诊患者抗菌药物处方比例为16.56%,抗菌药物的使用以全身用药及全身联合局部给药为主,局部用药为辅;在品种选择上以喹诺酮类滴耳液,第一、第二代头孢菌素为主,同时克拉霉素的使用也占据了重要地位;90%以上全身使用抗菌药物的疗程在2周以内,长疗程使用的抗菌药物以克拉霉素为主。结论:我院耳鼻喉科门诊患者抗菌药物处方比例低于原卫生计生委对于综合医院的规定。应重视长程口服克拉霉素患者的用药教育和细菌耐药性监测工作。
英文摘要:
      ABSTRACT Objective: To investigate the utilization of antibiotics in outpatient department of otolaryngology and provide the basis for comparison and management. Methods:A cross sectional survey was conducted to investigate the use of antibacterial drugs prescribed in the otolaryngology outpatient department for 1 month. An investigation of distribution of administration routes, selection of varieties, consumption and duration of antibiotics, dosage regimen and duration of clarithromycin tablets was conducted. Results:The proportion of antibacterial prescriptions including topical usage was 16.56%, systemic administration and systemic combined with local administration were the main route, supplemented by local administration. Quinolones ear drops and first or second generation cephalosporin were mainly used, clarithromycin also played an important role. 90% of the duration of systemic administration antibiotics were within 2 weeks, clarithromycin was the main antibiotics for a long duration. Conclusion: The percentage of antimicrobial application in the outpatient department of otolaryngology in our hospital is lower than the regulations for general hospitals by the health and family planning commission. The patient education and bacterial resistance monitoring should be given to the patients of long term oral administration of clarithromycin.
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