|
| 北京地区2013～2018年替加环素不良反应回顾性分析 |
| Retrospective Analysis of ADR Induced by Tigecycline in Beijing Area During 2013-2018 |
| |
| DOI： |
| 中文关键词: 替加环素 药品不良反应 报告 安全用药 |
| 英文关键词:Tigecycline Adverse drug reactions Report Safety medication |
| 基金项目: |
|
| 摘要点击次数: 1020 |
| 全文下载次数: 726 |
| 中文摘要: |
| 摘 要 目的：了解替加环素不良反应发生的特点，为临床安全使用替加环素提供参考。 方法：调取国家药品不良反应（ADR）监测系统收集的2013～2018 年北京地区替加环素ADR报告，对其发生的特点及相关因素进行回顾性分析。 结果：统计时间内，共收到49份怀疑与替加环素有关的ADR报告。其中60岁以上老年患者居多，占67.35％；临床表现复杂多样，主要ADR累及系统为血液系统（36.21%）、消化系统（20.69%）、皮肤软组织及附件（17.24%）。ADR发生在2～6 d内占40.82％，大多经停药或对症治疗后好转。 结论：临床合理使用替加环素可以减少其ADR 的发生。建议在使用该药时，对患者进行严密监护，以降低发生ADR的风险。 |
| 英文摘要: |
| ABSTRACT Objective: To understand the characteristics induced by tigecycline, and to provide reference for clinical safe and rational use of tigecycline. 〖WTHZ〗Methods:〖WTBZ〗According to the ADR reports of tigecycline collected by Beijng Center for ADR Monitoring from 2013 to 2018, the characteristics and related factors of the occurrence of tigecycline ADR were analyzed retrospectively. 〖WTHZ〗Results:〖WTBZ〗During the statistical period, 49 ADR reports suspected to be related to tigecycline were received. Of 49 ADR cases, the incidence of ADR in the elderly patients was higher than young patients, over 60 years old (67.35%). Clinical manifestations are complex and diverse. The main ADR involvement systems are blood system (36.21%), digestive system (20.69%), skin and soft tissue and accessories (17.24%). ADR occurred within 2 6 days, accounting for 40.82%. Most of them would be better after stopping drug or symptomatic treatment. 〖WTHZ〗Conclusion:〖WTBZ〗 Rational clinical use of tigecycline can reduce the incidence of ADR. It is suggested that patients should be closely monitored in order to reduce the risk of ADR. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
