ABSTRACT Objective: To strengthen the management of key monitoring drugs in hospitals, reduce drug expense under the new medical reform, and improve the management level of clinical application of drugs in hospitals. Methods:By setting up long acting and effective management system for the rational use of drugs, such as covering pharmacists comprehensive, reviewing combined with health insurance policy daily, three level of training, making appointments with pharmaceutical factories, publishing the withdrawal messages, optimizing pharmaceutical scheme, establishing informatization control rules and setting up performance appraisal measures. The proportions of drug expense, key monitoring drug expense, essential drug usage, unreasonable drug usage and the first ten drug order before and after management were analyzed. Results:Comparing before management, the proportion of drug expense after management decreased from 45.52% to 32.46%, a decline of 28.69%; the proportion of key monitored drugs decreased by 37.03%; the proportion of essential drug usage increased by 6.64%; the proportion of unreasonable drug usage decreased by 41.35%, and the intensity of antibacterial drug usage down 11.6%. The per capita number of inpatient drug varieties dropped from 8.17 to 6.96, a drop of 14.81%. Among the top 10 drugs, the guidelines recommended treatment drugs appeared. Conclusion:Hospital should promote the key monitoring of drug management, reduce drug expense, improve the level of rational drug usage by withdrawing drug, targeted restricting prescription, information controlling, adjusting drug catalogue, reviewing and training for the rational use of drugs combination with hospital drug use characteristics, the local drug regulatory measures and medical insurance policy. |