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| 痰热清注射液联合西医常规治疗对慢性阻塞性肺疾病急性加重期患者疗效及红细胞免疫功能影响 |
| Efficacy of Tanreqing Injection on Clinical Curative Effect and Erythrocyte Immune Function of Acute Exacerbation of Chronic Obstructive Pulmonary Disease |
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| DOI： |
| 中文关键词: 痰热清注射液 慢性阻塞性肺疾病，急性加重期 临床疗效 肺功能 红细胞免疫功能 |
| 英文关键词:Tanreqing injection Chronic obstructive pulmonary disease, acute exacerbation Clinical efficacy Pulmonary function Erythrocyte immune function |
| 基金项目:武汉市卫生计生科研基金项目（编号：WZ16Z07）；湖北省第三人民医院“提升人才计划”项目 |
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| 中文摘要: |
| 摘 要 目的：探究痰热清注射液联合西医常规治疗对慢性阻塞性肺疾病急性加重期（AECOPD）患者的临床疗效和红细胞免疫功能的影响，为AECOPD的治疗提供借鉴。方法：130例AECOPD的患者随机分为观察组和对照组，每组各65例。观察组采用痰热清注射液联合西医常规治疗，对照组采用西医常规治疗，观察两组临床疗效，比较治疗前后两组患者肺功能以及红细胞免疫功能变化。结果：剔除脱落病例后，每组各60例患者完成治疗。观察组总有效率达96.67%，明显优于对照组的80.00%（P＜0.05）。治疗后，两组肺功能指标和红细胞免疫功能均较治疗前明显改善(P＜0.05)；且观察组FEV1、FEV1/FVC以及红细胞免疫功能指标均显著优于对照组(P＜0.05)。结论：痰热清注射液联合西医常规治疗，能提高AECOPD患者红细胞免疫功能，改善AECOPD患者临床症状，其疗效优于西医常规治疗。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinical effect of Tanreqing injection combined with routine western medicine treatment on patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and the influence on erythrocyte immune function, so as to provide reference for the treatment of AECOPD. Methods:130 patients with AECOPD were randomly divided into observation group and control group, 65 cases in each group. The observation group was treated with Tanreqing injection combined with routine western medicine, while the control group was treated with routine western medicine. The clinical efficacy of the two groups was observed, and the changes of pulmonary function and erythrocyte immune function of the two groups before and after treatment were compared. Results:After eliminating the patients withdrew, there were 60 cases in each group. The total effective rate of the observation group was 96.67%, which was significantly better than 80.00% of the control group (P<0.05). Before treatment, there was no significant difference in baseline data, pulmonary function and erythrocyte immune function between the two groups (P>0.05); after treatment, both groups had optimal clinical efficacy, and the pulmonary function and erythrocyte immune function were significantly improved (P<0.05); the improvement of erythrocyte immune function, FEV1,FEV1/FVC in the observation group were better than that in the control group (P<0.05). Conclusion:Tanreqing injection combined with routine western medicine treatment can improve erythrocyte immune function and clinical symptoms of patients with AECOPD, and its curative effect is better than routine western medicine treatment. |
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