| ABSTRACTThrough analyzing and discussing a case of using vancomycin for the hemodialysis patient with complicated urinary tract infection, in which the clinical pharmacist participated, to share the experiences in tanking vancomycin for anti infective treatment of high flux hemodialysis with complicated urinary tract infection. The clinical pharmacists made the individualized vancomycin medication based on the common pathogens and drug resistance in complicated urinary tract infections, PK/PD parameters of vancomycin in high flux hemodialysis, and serum drug concentration monitoring. By adjusting the drug treatment program, the vancomycin related serum drug concentration of the patient reached the range of therapeutic window, the infection was controlled, and there was no renal toxicity and other adverse reactions related to vancomycin in the treatment process. Therefore, it was proved that, in the drug treatment of special hemodialysis patients with renal failure, the clinical pharmacists can assist doctors in optimizing the treatment program to improve the clinical drug treatment effect and promote the rational clinical medication. |
